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Avtar Roopra Selected Research

RE1-silencing transcription factor

9/2015Type 1 Insulin-Like Growth Factor Receptor/Insulin Receptor Substrate 1 Signaling Confers Pathogenic Activity on Breast Tumor Cells Lacking REST.
12/2012A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease.
12/2012Epigenetics and epilepsy.
7/2012Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors.
6/2010The transcription factor REST is lost in aggressive breast cancer.

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Avtar Roopra Research Topics

Disease

13Neoplasms (Cancer)
01/2021 - 11/2006
8Epilepsy (Aura)
01/2019 - 11/2006
5Seizures (Absence Seizure)
01/2019 - 11/2008
5Breast Neoplasms (Breast Cancer)
09/2015 - 06/2010
2Autistic Disorder (Autism)
01/2019 - 01/2013
2Inborn Genetic Diseases (Disease, Hereditary)
01/2019 - 01/2013
2Tuberous Sclerosis (Bourneville's Disease)
01/2019 - 01/2013
2Nervous System Diseases (Neurological Disorders)
01/2019 - 11/2006
1Type 2 Diabetes Mellitus (MODY)
08/2021
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
08/2021
1Inflammation (Inflammations)
08/2021
1Neurologic Manifestations (Neurological Manifestations)
01/2019
1Sudden Unexpected Death in Epilepsy
01/2018
1Uterine Cervical Neoplasms (Cancer of the Cervix)
10/2017
1Carcinogenesis
10/2017
1Status Epilepticus (Complex Partial Status Epilepticus)
01/2017
1Intellectual Disability (Idiocy)
01/2013
1Stroke (Strokes)
01/2013
1Ischemia
01/2013
1Infarction (Infarctions)
01/2013
1Glioblastoma (Glioblastoma Multiforme)
12/2012
1Chromosomal Instability (Chromosome Stability)
08/2012
1Aneuploidy (Aneuploid)
08/2012
1Lung Neoplasms (Lung Cancer)
06/2010
1Temporal Lobe Epilepsy
11/2006
1Drug Resistant Epilepsy
11/2006

Drug/Important Bio-Agent (IBA)

5Transcription Factors (Transcription Factor)IBA
08/2021 - 07/2012
5RE1-silencing transcription factorIBA
09/2015 - 06/2010
4Messenger RNA (mRNA)IBA
09/2015 - 06/2010
3RNA (Ribonucleic Acid)IBA
08/2021 - 07/2012
3Proteins (Proteins, Gene)FDA Link
09/2015 - 01/2013
3Deoxyglucose (2 Deoxy D glucose)IBA
02/2010 - 11/2006
3Anticonvulsants (Antiepileptic Drugs)IBA
04/2009 - 11/2006
2trans-sodium crocetinate (crocetin)IBA
01/2019 - 01/2013
2Estrogens (Estrogen)FDA Link
10/2017 - 01/2012
2ElementsIBA
09/2015 - 12/2012
2MicroRNAs (MicroRNA)IBA
01/2013 - 01/2013
2ChromatinIBA
12/2012 - 11/2006
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1Histone Deacetylase InhibitorsIBA
01/2019
1Enhancer of Zeste Homolog 2 ProteinIBA
01/2019
1Sirtuin 1IBA
01/2018
1CytokinesIBA
10/2017
1LigandsIBA
10/2017
1ChemokinesIBA
10/2017
1Kainic Acid (Kainate)IBA
01/2017
1Pilocarpine (Ocusert)FDA LinkGeneric
01/2017
1Insulin Receptor Substrate ProteinsIBA
09/2015
1Somatomedin Receptors (Somatomedin Receptor)IBA
09/2015
1AgarIBA
09/2015
1EpitopesIBA
05/2015
1Carrier Proteins (Binding Protein)IBA
05/2015
1RNA-Binding Proteins (RNA-Binding Protein)IBA
05/2015
1Protein Isoforms (Isoforms)IBA
05/2015
1theasinensin AIBA
01/2013
1Small Interfering RNA (siRNA)IBA
01/2013
1Oxygen (Dioxygen)IBA
01/2013
1Glucose (Dextrose)FDA LinkGeneric
01/2013
1PoisonsIBA
08/2012
1Pharmaceutical PreparationsIBA
01/2012
1AnthracyclinesIBA
01/2012
1Complement System Proteins (Complement)IBA
01/2012
1CarcinogensIBA
01/2012
1Phenobarbital (Luminal)FDA Link
01/2012
1Estrogen ReceptorsIBA
06/2010
1Chromogranin AIBA
06/2010
14-Aminopyridine (4 Aminopyridine)FDA Link
04/2009
1Pentylenetetrazole (Metrazol)IBA
04/2009
1CarbohydratesIBA
04/2009
1BicucullineIBA
04/2009

Therapy/Procedure

4Therapeutics
01/2021 - 11/2006
2Ketogenic Diet
04/2009 - 11/2006
1Lasers (Laser)
01/2017
1Drug Therapy (Chemotherapy)
12/2012